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and Poster sessions: |
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Talks will be held in
lecture_hall_14_(HS14)
and
lecture
hall 15 (HS15) |
Please
register and submit your abstracts (talk or poster) using the internet
based ConfTool registration and submission platform:
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=> Registration.qPCR-dPCR-NGS-2019.net
=> Submission.qPCR-dPCR-NGS-2019.net
=> Abstract
submission deadline for "Late Breaking Posters" is extended to 1st
March
2019
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Main
topic: Next Generation Biomarkers
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Title
(preliminary title)
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Speakers
Papers
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KEYNOTE
LECTURE:
CARL
WITTWER
Professor,
Department of Pathology, University of Utah, US, Adjunct
Professor, Biomedical Engineering, University of Utah, US
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Fast qPCR technologies and
the future of molecular diagnostics.
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HARALD SCHMIDT
Professor & Head
of Department of Pharmacology & Personalised Medicine, Faculty of
Health, Medicine & Life Science, Maastricht University, The
Netherlands
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The
end of medicine as we know it. |
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STEPHEN A. BUSTIN
Professor of Molecular Medicine, Postgraduate Medical Institute,
Faculty of Health, Social Care & Education, Anglia Ruskin
University, UK
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mRNA As A Forensic Target - A Bridge Too
Far?
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NICOLAS AUTRET
PhD, Covaris Europe, R&D, Brighton Office Campus, Woodingdean,
Brighton, UK
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From Next Generation Sequencing to Next
Generation Biomarkers -- How Adaptive Focused Acoustics® is
Transforming High-throughput Biology and Multi-omics Analyses.
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Main topic: Liquid Biopsy &
Circulating NAs
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KEYNOTE
LECTURES:
ANDERS STAHLBERG
Prof. and Senior
Scientist, Sahlgrenska Cancer Center, University of Gothenburg, Sweden
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Cancer diagnostics
using liquid biopsies and digital sequencing.
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JO VANDESOMPELE
Prof. at Center for Medical Genetics Ghent, Ghent University, Ghent,
Belgium, Biogazelle, 9052 Zwijnaarde, Belgium
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Exploiting
RNA in Liquid Biopsies for Precision Medicine Purposes.
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STEFAN HOLDENRIEDER
Prof, MD, Acting Director of Institute of Laboratory Medicine, German
Heart Centre Munich, Technical University of Munich, Germany
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Clinical application of circulating nucleic
acid diagnostics in liquid biopsy. |
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MICHAEL W. PFAFFL
Prof. of Molecular Physiology, Animal Physiology & Immunology, TUM
Weihenstephan, Germany
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Liquid Biopsy -- Exosomal microRNA
Biomarker Signatures in Clinical Diagnostics.
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BETTINA
STRAUCH
PhD, Agilent Technologies, R&D,
Braunschweig, Germany
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New Developments in Sample Quality Control
- Focus on Cell-free DNA.
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Main topic: Multi-Omics &
Integrative Big Data Analysis
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KEYNOTE
LECTURE:
JAN
BAUMBACH
Prof. at Chair of Experimental Bioinformatics, TUM School of Life
Sciences Weihenstephan, Technical University of Munich, Freising,
Germany
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Systems
Medicine - or - What I learned about Arnold Schwarzenegger while
studying breast cancer survival.
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THOMAS WILCKENS
CEO InnVentis Ltd., Brooks Keret, Kadima, Israel
Founder "Precision Medicine & Big Data in Life Science" on LinkendIn
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Deciphering inflammation and autoimmunity
with longitudinal multi-omics analysis.
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JO VANDESOMPELE
Prof. at Center for Medical Genetics Ghent, Ghent University, Ghent,
Belgium, Biogazelle, 9052 Zwijnaarde, Belgium
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HTPathwaySeq
-- a Novel Application for High-throughput RNA Sequencing Based Pathway
Phenotyping.
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Main topic: MicroGenomics &
Single-cells Diagnostics
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KEYNOTE
LECTURE:
VLADIMIR BENES
PhD, Head of GeneCore @ EMBL, Heidelberg, Germany
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Single-cell transcriptomics -- are we there
yet?
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MICHAELA ASP
Department of Gene Technology, KTH Royal Institute of Technology,
Science for Life Laboratory, Stockholm, Sweden
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Spatial
Transcriptomics - Bridging histology and RNA sequencing. |
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RADEK SINDELKA
PhD, Gene Expression Laboratory, IBT, Institute of
Biotechnology CAS, Vestec, Czech Republic
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Spatial analysis of transcriptome and
proteome during early development.
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KANEV KRISTIYAN
PhD candidate, Animal Physiology & Immunology, TUM Weihenstephan,
Germany
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Tailoring scRNA-Seq to meet the challenges
of primary murine cytotoxic T-cells.
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PATRICK ROELLI
PhD candidate, Animal Physiology & Immunology, TUM Weihenstephan,
Germany
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dropSeqPipe - from raw data to a single
cell readcount table.
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CHRISTOPHE LANCRIN
EMBL Monterotondo - Rome, Adriano Buzzati-Traverso
Campus, Monterotondo (RM), Italy
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Using
single-cell transcriptomics to decipher the formation of blood stem
cells. |
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ISEV Satellite
Session:
Extracellular Vesicles & Exosome Diagnostic Biomarkers
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supported
by 
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KEYNOTE
LECTURE:
KENNETH
W. WITWER
Assistant Professor of Molecular and Comparative Pathobiology,
Neurology, Cellular and Molecular Medicine, The Johns Hopkins
University School of Medicine, Baltimore, USA;
Secretary General, International Society for Extracellular Vesicles
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Standardization in EV and exRNA research --
MISEV and beyond.
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HIDETOSHI
TAHARA
Professor & Vice
Dean, Department of Cellular and Molecular Biology, Institute of
Biomedical & Health Sciences, Hiroshima University, Japan
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Characterization
of extracellular vesicles (EVs) derived exRNA in cancer using NGS. |
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BERND GIEBEL
PhD, PD, Insitute for Transfusion Medicine, University Hospital Essen,
Essen, Germany
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Extracellular vesicles: potential new tools
for diagnostics and therapies?
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CHRISTIAN PREUSSER
PhD, Institute of Biochemistry, Justus-Liebig-University, Giessen,
Germany
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Circular
RNAs in EVs - a novel class of released noncoding RNAs. |
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ESTHER NOLTE-T HOEN
Assistant Professor, Department of Biochemistry and Cell Biology, Cell
Biology, University of Utrecht, The Netherlands
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Distribution of non-coding RNA types over
EV and other carriers in plasma.
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Digital
PCR
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ALEXANDRA WHALE
PhD, Molecular and Cell Biology Team, LGC, Teddington, UK
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Fundamentals
of multiplexing with digital PCR.
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CLAUDIA FELICI
PhD, Department of Biomedical Sciences and Human Oncology, Section of
Medical Oncology, University of Bari Aldo Moro, Italy
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Molecular characterization by ddPCR of in
vitro differentiated oocyte-like cells from oogonial stem cells.
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AFIF ABDEL NOUR
Associate Professor in Nutrigenetics, Faculty of Agricultural and Food
Sciences, Holy Spirit University of Kaslik (USEK), Lebanon
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Eight years later this is what ddPCR
offered to science.
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KATHARINA LÜHRIG
PhD, Scientist Research & Development, BIOTECON Diagnostics GmbH,
Potsdam, Germany
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Highly multiplexed detection of GMOs in
food samples by Crystal Digital PCR.
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CHRISTOPH KÖNIG
PhD, Application Scientist Manager, Nanostring, R&D, Fairview
Avenue N, Seattle, Washington, USA
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Resolving Translational Oncology Research
Challenges with NanoString Direct Digital Gene Expression Analysis
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CHRIS PERKINS
CEO, Dropworks Inc, Boulder, Colorado, USA
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Serial
Flow Digital Droplet PCR, a New Paradigm!
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Non-coding
RNAs -- microRNA, small RNAs, long non-coding RNAs
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KEYNOTE LECTURE:
PIETER
MESTDAGH
Prof. at Center for Medical Genetics, Ghent University,
Cancer Research Institute Ghent, Ghent University, Belgium
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The RNA-Atlas -- a single-nucleotide resolution map of the human
transcriptome.
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TIM KACPROWSKI
PhD, Chair of Experimental Bioinformatics, TUM School of Life Sciences
Weihenstephan Technical University of Munich, Freising, Germany
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Circulating
miRNAs as potential biomarkers. |
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Next
Generation Sequencing (NGS)
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JUSTIN O’GRADY
Lecturer in Medical Microbiology, Norwich Medical School, University of
East Anglia, Norwich, UK
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Towards
a universal diagnostic test for infection using rapid nanopore
metagenomics.
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PETER ANDROVIC
PhD, Gene Expression Laboratory, IBT, Institute of Biotechnology CAS,
Vestec, Czech Republic
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Getting more out of RNA-Seq data:
transcriptomic analysis of ischemic stroke.
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FRAUKE COPPIETERS
Center for Medical Genetics, Ghent
University,
Cancer Research Institute Ghent, Ghent University, Belgium
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PCR Based Target Enrichment For Variant
Confirmation, Gene Panels And Multiplex PCR Sample Tracking In A Whole
Exome Sequencing Workflow.
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DAVE SCHUSTER
PhD, Director R&D, Quanta BioSciences, Perry Parkway, Gaithersburg,
MD, USA
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Directed Evolution of Enzymes for
Streamlined and Reliable RT-qPCR and NGS Workflows.
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CHRISTOPHER D'JAMOOS
PhD, Promega Corporation, 2800 Woods Hollow Rd. Madison, WI, USA
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QC Measurements for Predicting Downstream
NGS Success with FFPE and Circulating Cell-Free DNA Plasma Samples.
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qPCR & NGS Data
Analysis
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JAMES BRIAN BYRD
Asst. Professor, Cardiovascular Medicine, MD, MS (Clinical
Investigation), FAHA, FACC, University of Michigan, US
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Normalizing Urinary Extracellular Messenger
RNA Biomarkers: Theoretical Considerations and a Review of Experimental
Findings.
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DAVID LANGENBERGER
CEO, Phd, ecSeq Bioinformatics GmbH, Leipzig, Germany
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Tiled
Amplicons Panels in NGS-Based Genetic Testing.
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PHILIP DAY
PhD, Division of Evolution & Genomic Sciences, Manchester Institute
of
BiotechnologyFaculty of Science and Engineering, University of
Manchester, UK
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GeneGini: Assessment via the Gini
Coefficient of Reference "Housekeeping" Genes and Diverse Human
Transporter Expression Profiles.
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MAURICE JB van
der HOFF
Associate Professor, Department of Medical Biology, Amsterdam UMC, The
Netherlands
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Integration
of DNA melting curve analysis in qPCR data analysis.
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Advanced
Molecular
Diagnostics in Life Science
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KEYNOTE LECTURE:
MIKAEL
KUBISTA
Prof. of Biotechnology, BTU, Czech Academy of Sciences &
TATAA Biocenter, Sweden
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New Advances in Two-Tailed
PCR.
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MARY ANNA VENNERI
Professor, Department of Experimental Medicine, Sapienza University of
Rome, Italy
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Impact
of endogenous and exogenous alterations of glucocorticoids on
the derangement of clock genes in peripheral mononuclear cells.
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PATRICK GÜRTLER
PhD, Bavarian Health and Food Safety Authority, Molecular Biology Unit,
Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit (LGL),
Oberschleissheim, Germany
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Evolution
of GMO analysis – from qPCR to NGS. |
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JESUS AQUILES SANCHEZ
PhD, Principal Scientist at ThermaGenix, Inc, MA, USA
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A Portable, Accurate, and Cost-Effective
Strategy for Rapid On-Site Authentication and Characterization of
Commercially Important Species and Pathogens Using Bio Molecular
Systems’ MIC qPCR Cycler.
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MIQE
& Quality Management & Standardisation Strategies in Molecular
Diagnostics
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KEYNOTE
LECTURE:
JIM HUGGETT
PhD, Science Leader, Nucleic Acid Metrology, LGC, Teddington,
UK
Senior Lecturer, Analytical Microbiology, University
of Surrey, UK
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Biometrology, what is it and what could it mean for biomolecular
research?
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STEFAN RÖDIGER
Faculty of Natural Sciences, Brandenburg University of Technology
Cottbus-Senftenberg, Senftenberg, Germany
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The
PCRedux Package: Fundamentals for the Automatic Classification of
Quantitative PCR Amplification Curves - a Biostatistical Approach.
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MASSIMO SANTORO
PhD, IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy
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Methylation-sensitive high resolution
melting (MS-HRM): a sensitive and specific method for high-throughput
assessment of methylation.
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JAN RUIJTER
PhD, Department of Medical Biology, Amsterdam UMC, The Netherlands
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Why
reporting Cq or delta-Cq values is senseless. |
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PETER ROSSMANITH
Dr. rer. nat., Institute of Milk Hygiene, Milk Technology and Food
Science of Vetmeduni Vienna, Austria
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Intergrated
and Alternative Validation in qPCR Assay Development. |
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SERGEY KOVALENKO
R&D, BIORON
Diagnostics GmbH, Ludwigshafen,
Germany
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SD DNA Polymerase: A New Tool for Variety
of Molecular Biology Applications.
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Mikael Kubista & Amin Forootan
MultiD & TATAA Biocenter Sweden, Göteborg, Sweden
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GenEx
– The Ultimate Software for Analysis of Transcriptomic Data.
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ANDREAS
UNTERGASSER
PhD, University of Heidelberg, Heidelberg, Germany
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RDML v1.3 as a vendor independent data exchange format for
digital PCR.
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